The ChAmPion Process transforms human placental membranes obtained from consented Caesarean sections into a dehydrated chorioamniotic allograft. The proprietary and validated ChAmPion process maintains the native configuration of the amnion and chorion layers throughout the process to preserve interstitial constituents, such as hyaluronan, that are lost if membranes are separated. The removal of the non-immune privileged maternal decidua cells is performed to enhance the physical and biological uniformity of the tissue. The resultant membranes are then processed utilizing benign processing solutions, with no detergents, to maintain the integrity of the amniotic epithelium and biological composition.
After liquid phase processing, the chorioamniotic membranes are subjected to a proprietary compacting and dehydration process that yields allografts with dense, uniform, and flexible physical properties coupled with extremely favorable handling characteristics. Sidedness is generated during the drying process without loss of material so that the amnion and chorion surfaces can be easily distinguished. The dehydration process yields allografts with low moisture content, which is maintained during packaging to ensure stability at room temperature storage.1
Rehydration of a ChAmPion processed allograft delivers a flat and easy to handle membrane that conforms to any surface.