Project Description


The Misonix SonicOne O.R. System, now with SonicVac (as shown above) is an innovative ultrasonic surgical debridement system that allows surgeons to address the challenges chronic wounds present to them, the patient, and the health-care system. SonicOne O.R. establishes a new standard in surgical wound bed preparation, an essential first step in the wound healing process.


Top-down debridement by utilizing SonicOne.

Top-Down Wound Debridement Means Better Outcomes

SonicOne O.R. utilizes ultrasonic technology in the form of a debridement modality which provides safe and effective removal of all nonviable tissue while safely preserving healthy structures. Sharp and non-distinct debridement techniques often result in inadvertent resection of viable tissue planes. The precision available with the SonicOne O.R. allows for surgical debridement layer by layer from superficial to deep while protecting underlying viable tissues.

SonicOne O.R. with SonicVac is the Only Wound Debridement Device that Combines Aspiration with Ultrasonic Debridement

SonicVac combines the advantages of vacuum aspiration with the precision and power of ultrasonic debridement for better outcomes.
• Significantly reduces spray dispersion1
• Captures used irrigate in addition to other fluids from the wound site1
• Removes disrupted debris from the field1

1.“The clinical implications of a new wound debridement device that combines low frequency direct contact ultrasound and vacuum aspiration.” Mark S. Granick M.D., Michael Baruch M.D., Wayne J. Caputo M.D., Paul M. Glat M.D.

Preservation of Healthy Tissue and Vital Structures

The SonicOne O.R. provides surgeons a safe and effective means of surgical soft and hard tissue management. Utilizing low frequency, high intensity ultrasound, the SonicOne O.R. titanium tips vibrate at 22.5 kHz. This precise vibration creates mechanical energy that is transferred to tissue, causing molecules to oscillate. Micro-sized gas bubbles created in tissue and surrounding fluids create bubbles that collapse (implode), which results in destruction of tissue close to the bubbles. This transient cavitation emulsifies devitalized tissue while the membranes of healthy tissue simply move with the oscillation.

Pre-debridement of foot.


Post-debridement using SonicOne with SonicVac.

Effectively Lyses and Removes Bacteria and Biofilms

Due to the ultrasonics phenomenon of transient cavitation, the gas-filled bubbles created by the SonicOne O.R. undergo rapid expansion followed by collapse. The turbulence created by the imploding gas bubbles may be one mechanism by which destruction of bacteria and biofilm occurs. “Post-treatment a log 5 reduction in bacterial count was seen as a result of the low frequency ultrasonic debridement. Three of the five samples post treatment showed a bacterial count of zero. The cultures and quantitative bacterial cultures indicate the ability for SonicOne ultrasonic debridement to reduce bacterial load in a variety of wound types and with a broad spectrum of bacteria present.”1

lyses 1

Pre-debridement of tibia

lyses 2

Post-debridement using SonicOne with SonicVac.

1.“Surgical Debridement with SonicOne; an initial look at the bacterial load pre and post low frequency direct contact ultrasound.” Daria Abolghasemi, D.O., Karen D. Szymanski, D.O., Michael Baruch M.D., Jamshed Zuberi M.D.

Consistently Maximizes Wound Bed Preparation

The therapeutic effects of low frequency ultrasound on wound bed preparation and healing is well documented in the literature. Acoustic micro-streaming and cavitation are the principal effects that drive the cascade of healing activity. Acoustic streaming has been shown to alter cell membrane permeability and second messenger activity, which in turn may result in increased protein synthesis, degranulation of mast cells, and increased production of growth factors. It has been shown that patients within a study treated with SonicOne Ultrasound for recipient site wound bed preparation with subsequent skin graft have a 90% take of split thickness skin graft.1

Pre-debridement of foot ulcer.

Pre-debridement of foot ulcer.

Post debridement pre graft application.

Post debridement pre graft application.

Post graft placement.

Post graft placement.

1. “Split Thickness Skin Graft Incorporation after Ultrasonic Debridement for Wound Bed Preparation in Diabetic Foot Wounds.” Sean M. Betesh, DPM, Michael I. Gazes, DPM, MPH, Peter Blume, DPM, FACFAS.

Reduces Blood Loss

SonicOne O.R. has demonstrated reduced blood loss when compared to standard excision methods.1

reduces 1   reduces 2   reduces 3

1.“Ultrasonic Tangential Burn Excision Reduces Blood Loss.” Abraham P. Houng M.D., Sylvia J. Petrone M.D., Robin A. Lee M.D., Christina Lee M.D., Michael A. Marano M.D.

SonicVac Wide Hatch Probe MXC X2 VAC sm


The Only Wound Debridement Device that Combines Aspiration with Ultrasonic Debridement

SonicVac combines the advantages of vacuum aspiration with the precision and power of
ultrasonic debridement for better outcomes.

• Eliminates vapor dispersion
• Captures used irrigate in addition to other fluids from the wound site
• Removes disrupted debris from the field



The Cylindrical tip can effectively penetrate deep, narrow wounds that are typically very difficult to access with
a scalpel, without making the wound much larger. The tip’s cylindrical shape, with radially positioned coarse
surfaces, can be highly aggressive when debriding tunneling wounds or sinus tract walls, in addition to surface
debridement of larger areas.



The Curette Style Tip provides a curved contact surface that can be used to saucerize (angle) the wound
edges and provide direct ultrasonic energy to the wound bed. The rounded surface also allows for precise
engagement of specific areas that may require excision.

Hatch Titanium Probe MXC X1 sm


This tip has a large hatched contact surface. The design of this tip allows for a very aggressive debridement.
This tip is versatile and can be used for general large area debridement,
while also capable of performing ultrasonic debridement of necrotic bone and thick eschar.









SonicOne O.R. Large Blade Serrated MXC BLADE LS sm


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The Surgical Debridement Tips are designed to specifically address the needs of different wound types.
The unique shape of each tip allows the surgeon to choose the most appropriate tip based upon the wound.
All of the ultrasonic surgical tips are designed for direct contact with the wound surface to induce cavitation
at the tip/tissue interface. Necrotic tissue, with weakened and inelastic cell bonds is easily removed, while healthy
tissue with stronger and elastic bonds is spared, providing maximum wound debridement efficiency.
The combination of tip shape and amplitude settings offer the surgeon a full range of options to match specific
debridement requirements; from the removal of slough or fibrin, to a full excisional debridement.
Clinical applications include, but are not limited for use in, the debridement of wounds, including diabetic foot
ulcers, venous ulcers, pressure sores, burns and bone.